Description

Zopiclone/ Sleeping Aid 7.5mg@20tabs by SandoxPharma Pty SA

Each tablet contains 7.5mg of Zopiclone and also 78.50mg Lactose Monohydrate

This is a true pharmaceutical product. **This product has been repackaged

Therapeutic indications:
Short term treatment of insomnia, including difficulties in falling asleep, nocturnal awakening and early awakening, transient, situational or chronic insomnia, and insomnia secondary to psychiatric disturbances, in situations where the insomnia is debilitating or is causing severe distress for the patient.

Long term continuous use is not recommended.

A course of treatment should employ the lowest effective dose.

Posology and method of administration:
Adults:
The recommended dose is 7.5mg zopiclone by the oral route shortly before retiring.
Elderly:
A lower dose of 3.75mg zopiclone should be employed to start treatment in the elderly. Depending on effectiveness and acceptability, the dosage subsequently may be increased if clinically necessary.

Contraindications:
Zopiclone 7.5mg tablets is contraindicated in patients with myasthenia gravis, respiratory failure, severe sleep apnoea syndrome, severe hepatic insufficiency and those people with a hypersensitivity to zopiclone or to any of the excipients. As with all hypnotics, Zopiclone 7.5mg tablets should not be used in children.

Driving:
It has been reported that the risk that zopiclone adversely affects driving ability is increased by the concomitant intake of alcohol. Therefore, it is recommended not to drive while taking zopiclone and alcohol concomitantly.

Pharmacodynamic properties:
Zopiclone is a hypnotic agent, and a member of the cyclopyrrolone group of compounds. It rapidly initiates and sustains sleep with reduction of total REM sleep and with preservation of slow wave sleep. Negligible residual effects are seen the following morning. Its pharmacological properties include hypnotic, sedative, anxiolytic, anticonvulsant and muscle- relaxant actions. These are related to its high affinity and specific agonist action at central receptors belonging to the “GABA” macromolecular receptor complex modulating the opening of the chloride ion channel. However, it has been shown that zopiclone and other cyclopyrrolones act on a different site to those of benzodiazepines including different conformational changes in the receptor complex.